Posts Tagged ‘Skin’

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PostHeaderIcon Dry Skin Care Techniques

There are so many forms of skin conditions as well as skin types that it is almost impossible for you to tell which one is better or worse. Some people with dry skin want it to be oiler, others who have oily skin wish that it was dryer. However, it does not matter what skin type you have, your skin will look healthier and hydrated with some simple dry skin care tips below.

 

Put in mind that dry skin care starts from within, thus if you hydrate yourself by drinking plenty of water and other fluids your skin is going to be much less dry. The skin draws most of its moisture from the layers on the bottom rather than from any topical cream you may use on the top layers. It is also important to note that when the body needs moisture and hydration it’s going to give this to the skin last; it is the last in priority.

The body hydrates the vital organs such as the heart and brain first, and then the major muscle groups, and then major systems such as the respiratory system and digestive system. Only the leftover hydration and moisture is then sent to the skin. Drinking water or fruit juice should be injected in your habit in dry skin care. For a change, try a drink mix like Crystal Light.

 

Moisturizing is also a part of dry skin care. And this means doing it religiously-day and night. It’s so important to use moisturizers at night because they don’t get rubbed off so easily and so the skin can absorb more, and because the body renews and regenerates itself during sleep. If you don’t add a moisturizer at night then you’re missing a big part of the skin care routine.

Using one in the morning before you head out is also important because moisturizers act as a protective layer between your skin and the elements in the atmosphere that can dry your skin such as pollutants and other irritants. You don’t need anything thick and goopy; a light moisturizer can be applied again during the day and it won’t mess up your makeup or be too obvious to others.

 

It is also recommended to use natural products. Using natural products also means less irritation to your face which is very important for dry skin care. When the face is irritated it uses up what natural oils it may have resulting in even worse dry skin. Some plain vitamin E oil that is available at most pharmacies and retail stores works very well even under makeup. This oil is usually very thick and so the skin can absorb it over time.

 

All these simple tips for your dry skin care!

 

Andy Immotna has been maintaining a number of premium membership internet marketing and niche websites that constantly provides members with highly valuable information. For more tips on skin care, checkout the skincare blog at http://skincare.knowledgealley.com

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PostHeaderIcon Skin Care – Czech Republic

Skin Care – Czech Republic

The trend in skin care is heading towards quality multifunctional products that can provide several effects together, such as nourishing, skin hydrating, firming and anti-ageing effect, sun protection etc. This demand relates to current lifestyles, with women preferring to use one cream rather than two or three. Also, natural products or products with natural ingredients are increasingly in demand. Ever more consumers are interested in the composition of skin care products.

Euromonitor International’s Skin Care Products in Czech Republic report offers a comprehensive guide to the size and shape of the market at a national level. It provides the latest retail sales data 2005-2009, allowing you to identify the sectors driving growth.

Forecasts to 2014 illustrate how the market is set to change.

Product coverage: Body Care, Facial Care, Hand Care

Data coverage: market sizes (historic and forecasts), company shares, brand shares and distribution data.

Why buy this report?
* Get a detailed picture of the Beauty and Personal Care industry;
* Pinpoint growth sectors and identify factors driving change;
* Understand the competitive environment, the market’s major players and leading brands;
* Use five-year forecasts to assess how the market is predicted to develop.

To know more and to buy a copy of your report to feel free to visit :
http://www.bharatbook.com/detail.asp?id=150205&rt=Skin-Care-Czech-Republic.html

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Skin Care – Ireland
http://www.bharatbook.com/detail.asp?id=150211&rt=Skin-Care-Ireland.html

Skin Care – Malaysia

http://www.bharatbook.com/detail.asp?id=150216&rt=Skin-Care-Malaysia.html

Or

Contact us at :

Bharat Book Bureau
Tel: +91 22 27578668
Fax: +91 22 27579131
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Bharatbook, the leading information aggregator. We facilitate and support the business information needs. With over millions of reports, you can get instant access and insights on the studies in you for market research, corporate / strategic planning by providing the latest information in the form of reports, journals, magazines and databases on varied industries like automotive, oil and gas, shipping, textiles, pharmaceuticals, energy, banking, finance, insurance, risk management, country intelligence, consumer & durable goods, chemical and more your areas of interest. Contact us at +91 22 27578668 / 27579438 or email info@bharatbook.com or our website www.bharatbook.com

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PostHeaderIcon Sensitive Skin Care

Being honest, all skin is really sensitive and needs sensitive skin care. Despite this, we often forget the importance of investing in skin care products that you have researched on and are actually effective.

I always think of sensitive skin as skin that is prone to infections that could lead to more serious conditions such as eczema; acne etc, and remember this; your skin can reflect how healthy our diet is.

What you need in cosmetic products is the use of ingredients that are safe ,effective and gentle on the skin. For instance, Active manuka honey is a unique type of honey from New Zealand which contains scientifically proven healing properties for the skin.

And these healing properties are due to its special enzymes that give it amazing antibacterial and anti oxidant properties. Having these properties in a product for skin sensitive like yours ensures that you are protected against any build up of harmful bacteria on your skin.

And the anti oxidant activity is there to ensure that it prevents oxidation through free radical damage.

And in addition to that active manuka honey stimulates the immune system making sure you are always protected.

What makes it even more special is the fact that even though a patented process to convert Active manuka honey to a powder has been developed for use in skin care products, it still does not lose any of its active ingredients. Hence, it is still very much effective.

And, Cynergy TK- a unique patented form of ‘bio-active’ keratin is a key ingredient when it comes to reducing redness associated with inflammation or sensitive skin.

It is at its most natural, therefore, any harmful side effects associated with synthetic ingredients will not affect you because of this.

Both Active manuka honey and Cynergy TK are examples of organic ingrients you should look out for in sensitive skin care products.

John Lexon is a dedicated researcher of important issues that affect skin and health.

Visit his skincare website now at http://www.abc-skin-and-health.info to learn more about the skin care products that he recommends after extensive research.

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PostHeaderIcon Skin Care – Mexico

Skin Care – Mexico

Innovation in terms of multipurpose formulations with high technology ingredients emulating cosmeceuticals, and segmentation in both mass and premium segment had an impact on skin care in 2009. Products with claims of anti-ageing, moisturising, sun protection, whiteners, firming and anti-cellulite were most popular in 2009.

Euromonitor International”s Skin Care Products in Mexico report offers a comprehensive guide to the size and shape of the market at a national level. It provides the latest retail sales data 2005-2009, allowing you to identify the sectors driving growth. Forecasts to 2014 illustrate how the market is set to change.

Product coverage: Body Care, Facial Care, Hand Care.

Data coverage: market sizes (historic and forecasts), company shares, brand shares and distribution data.

Why buy this report?
* Get a detailed picture of the Beauty and Personal Care industry;
* Pinpoint growth sectors and identify factors driving change;
* Understand the competitive environment, the market’s major players and leading brands;
* Use five-year forecasts to assess how the market is predicted to develop.

To know more and to buy a copy of your report to feel free to visit :
http://www.bharatbook.com/detail.asp?id=153333&rt=Skin-Care-Mexico.html

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Skin Care – Japan
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Skin Care – Romania

http://www.bharatbook.com/detail.asp?id=153339&rt=Skin-Care-Romania.html

Or

Contact us at :

Bharat Book Bureau
Tel: +91 22 27578668
Fax: +91 22 27579131
Email: info@bharatbook.com
Website: www.bharatbook.com
Follow us on twitter: http://twitter.com/3bbharatbook

Bharat Book Bureau facilitates companies to take the lead of their industry with best practice business strategies and intelligence, through a unique combination of published reports, databases, country reports, company profiles and customized research services.

Bharat Book Bureau provides strategic information tools to the executives, business analysts, and knowledge managers that will help them to probe into and support critical, timely business decisions and strategies.

Bharatbook, the leading information aggregator. We facilitate and support the business information needs. With over millions of reports, you can get instant access and insights on the studies in you for market research, corporate / strategic planning by providing the latest information in the form of reports, journals, magazines and databases on varied industries like automotive, oil and gas, shipping, textiles, pharmaceuticals, energy, banking, finance, insurance, risk management, country intelligence, consumer & durable goods, chemical and more your areas of interest. Contact us at +91 22 27578668 / 27579438 or email info@bharatbook.com or our website www.bharatbook.com

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PostHeaderIcon Facial Skin Care System

Revealed – Get The Best Facial Skin Care System

Everyone wants to look younger, at least when we get to a certain age we do but how do we go about getting the best facial skin care system that we can?

Do we have to research all the products available and take the time to see if they work or are we better to investigate the ingredients and make an informed choice from there?

For my money the more research you do the better and that is what I have done. You would be surprised at what goes into some of the popular brands. Some ingredients that have been commonly used for years have now been shown to be potentially harmful to your skin, not really something you want to cover your face in.

There are so many ingredients listed on the packaging that it is easy to become confused. There are however some key ingredients to be looking out for it you want to use the best facial skin care system.

Cynergy TK™ is a relatively new discovery in the anti aging world and it is taking it by storm.

It comes from New Zealand and has been proven to reduce wrinkles by encouraging your skin cells to start producing collagen and elastin at levels normally found in younger people.

Nano-Lipobelle H EQ10 is a powerful antioxidant. An antioxidant is required to help protect the new and existing cells from being attacked by harmful free radicals. So while your skin is being encouraged to up production you are helping out by protecting them. It is also highly nourishing and deeply penetrating.

Phytessence Wakame is an extract taken from Japanese sea kelp and helps the increase of hyaluronic acid in your skin returning it to levels found in much younger people.

If you do decide to do your own research as a start look into the ingredients I have mentioned above.

The facial skin system I now use contains all these ingredients and more and my skin has never looked or felt better.

Interested? Visit our website where you will get plenty of information and be able to make an informed choice to invest in the best facial skin care system we have ever come across.

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PostHeaderIcon Skin Care – Netherlands

Skin Care – Netherlands

Increased interest in prevention and personal appearance among Dutch consumers has underpinned healthy growth in skin care. Formulas that promote anti-ageing or hydrate boosted growth in the category in 2009. Despite the economic slowdown, growth was slightly lower than in 2008 but remained very dynamic, fuelled by continuing support in terms of new product developments and advertising, especially in the mass skin care segment. Dutch consumers, especially women, are aware that personal care is…

Euromonitor International”s Skin Care Products in Netherlands report offers a comprehensive guide to the size and shape of the market at a national level. It provides the latest retail sales data 2005-2009, allowing you to identify the sectors driving growth.

Forecasts to 2014 illustrate how the market is set to change.

Product coverage: Body Care, Facial Care, Hand Care.

Data coverage: market sizes (historic and forecasts), company shares, brand shares and distribution data.

Why buy this report?
* Get a detailed picture of the Beauty and Personal Care industry;
* Pinpoint growth sectors and identify factors driving change;
* Understand the competitive environment, the market’s major players and leading brands;
* Use five-year forecasts to assess how the market is predicted to develop.

To know more and to buy a copy of your report to feel free to visit :
http://www.bharatbook.com/detail.asp?id=153334&rt=Skin-Care-Netherlands.html

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Skin Care – Slovenia

http://www.bharatbook.com/detail.asp?id=153341&rt=Skin-Care-Slovenia.html

Or

Contact us at :

Bharat Book Bureau
Tel: +91 22 27578668
Fax: +91 22 27579131
Email: info@bharatbook.com
Website: www.bharatbook.com
Follow us on twitter: http://twitter.com/3bbharatbook

Bharatbook, the leading information aggregator. We facilitate and support the business information needs. With over millions of reports, you can get instant access and insights on the studies in you for market research, corporate / strategic planning by providing the latest information in the form of reports, journals, magazines and databases on varied industries like automotive, oil and gas, shipping, textiles, pharmaceuticals, energy, banking, finance, insurance, risk management, country intelligence, consumer & durable goods, chemical and more your areas of interest. Contact us at +91 22 27578668 / 27579438 or email info@bharatbook.com or our website www.bharatbook.com

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PostHeaderIcon Wrinkles Be Gone ? Skin Care Advice For All

In order to obtain glowing youthful skin it is important that you take care of your face and skin every day. In some cases you will find there are creams and moisturizers that will give you skin care benefits but you also need to look at your lifestyle and perhaps changes to your lifestyle to help you obtain the look you are trying to achieve. A lot f the skin care products you can purchase are not always effective and in some cases they are actually harmful to your skin.

Your skin is the largest organ in your body and your body uses not only to keep the rest of you inside but also to help stop any harmful ingredients getting to the inside. As we get older our skin looses its elasticity and that is when all those wrinkles will start to appear. Those wrinkles in turn make you start to look older so we often then decide it is time to take care of our skin however we should have been doing so from the very start.

When you are eating a well balanced diet including a lot of fruit and vegetables you are in fact feeding your skin as well. Make sure that you have a good mix of nutrients in your diet and avoid those fatty foods. If you are someone who gains and looses weight in large amounts regularly you will also find that all that stretching of the skin will leave you with loose skin which in turn turns into wrinkles as well.

Make sure that as part of your lifestyle you are also exercising your body but don’t forget your face. There are facial exercises you can do to help keep your skin supple and toned just as you can with the rest of your body. When you have strong muscles in your face these reduce the look of lines and wrinkles however you also want to ensure that you are taking the time to relax your face muscles as well. If you are a person who is always frowning try to change to make yourself aware of when you are doing this and STOP. Squinting is also a major cause of wrinkles, you do this when you are in bright sunlight but you also do this if you have bad eye sight so perhaps a pair of reading glasses is also a requirement!

The sun has a huge impact on skin care as well and you should try to stay out of the sun as much as you can, not only for the aging affects but due to possible http://en.wikipedia.org/wiki/Skin_cancer : skin cancer. If you are in the sun you must ensure that you are using a http://www.abso-bloody-lutely.com/Health/Beauty/Skin_Care : skin care product that has sun protection included in it to avoid further damage as much as you can.

Another thing that many of us do is we rub our eyes or and this can greatly increase the amount of wrinkles we are causing ourselves. Another tip is to try to always sleep on your back so that you are not squishing your face during the night. This is something you have to learn to do and will take a lot of time but you will find that sleeping on your back and not mushing your face into your pillow can reduce the amount of wrinkles that are appearing.

When considering purchasing skin care products you should keep the following in mind:

– Ingredients used in the product – try to avoid those with chemical substances and use those made from natural products.

– Does it contain allergens which can irritate your skin and lead to further problems?

– Is it going to moisturize your skin and does this product impact on different skin types?

– Is the product designed to reduce wrinkles by increasing collagen?

Last but not least, smoking is a great cause of wrinkles so if you are a smoker then giving up smoking will not only benefit your skin but also your entire health. Beauty skin care is important but skin care as a whole is an issue that everyone faces, males included and you can now find products that are designed for men and women that will in fact help you with your skin care regime so if you are serious about your skin care make sure you try to follow some of the advice listed above.

Written by omkarnaathgiri

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PostHeaderIcon Knowing About Natural Skin Care

Put simply, natural skin care is caring for your skin naturally and chemical free. Proponents of natural skin care “allows the skin to take care of itself (with any assistance from synthetic materials / chemicals). Natural Skin Care” inculcate habits is fantastic in the way they conduct their day day. Plenty of action natural natural skin care are basically exactly the same as body care in general.

So let’s see what these natural measures natual skin care.

Well the first addition to the most important natural skin care – ‘Drink plenty of water. Around 8 glasses of water is often a need every day. Water helps remove toxins in the body naturally. Assists in maintaining the interior of the body and promotes general well being great for all organs (not just the skin).

The cleanup is a more affordable care natural pure skin. Each day the shower, wearing clean clothes and sleep in a clean mattress / pillow are part of the cleanup. Shortly after all, clean skin may be the key to keeping the skin disorders at bay.

Regular physical exercise may be the next factor in the cards. Exercise increases blood flow which helps to acquire rid of toxins and maintain their health. Exercise also helps in the battle against stress, which is the worst enemy of a great being.

Healthy eating and drinking habits also are proposed natural skin care. Any type of food (oily food, for example) is known to cause acne and really should be avoided as much as possible. Your meal plan should be a healthy mix of different foods supply nutrients. Raw vegetables and fruits are recognized in offering freshness to your body and helps in the quest to get rid of toxins from the body.

A dream is also an excellent tool to maintain an excellent and well-being and the battle against anxiety. As a purely natural skin care, a delay of fantastic dream loosen the skin.

Overcoming Anxiety is an additional therapy natural skin care. Stress causes damage to the body in general and welfare. Drink plenty of water, the acquisition of a deep sleep and exercise has already been mentioned as pressure busters. Enjoy a hot bubble bath, listen to music and practice their favorite sport also beneficial methods of overcoming anxiety. Yoga is however a different way to beat the pressure, is fast becoming popular among the masses.

Avoid excessive contact with the sun (with the use of long sleeves, hats and umbrellas, etc.) is another technique pure natural skin care. Sunscreen lotions are also proposed as essential.

A lot of the homes produced conventional measures of a purely natural skin care products / are also identified to be quite successful. These measures are not only natural and easy to follow, but also economically reasonable.

Besides, a lot of good natural skin care are out there within the commercial market. These consist of items such as lavender oil, aloevera, etc, Which have no side effects.

Written by endu202
Iam Just a Blogger

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PostHeaderIcon Ebooks On Travel, Skin Care, Food And Health

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PostHeaderIcon Matching Emollient Neonatal Skin Care Product Selection With Changes in the Standard of Care

The Evidence-Based Clinical Practice Guideline for neonatal skin care, including a Neonatal Skin Condition Scale (NSCS), has been validated by the Association of Women’s Health, Obstetric and Neonatal Nurses (AWHONN) and the National Association of Neonatal Nurses (NANN). Within the Guidelines, the use of emollients is recommended for infants less than 32 weeks during the first 2-4 weeks. For infants younger than 30 weeks, gestational age emollient use is recommended to reduce excessive transepidermal water loss (e-TEWL).

Over a period spanning three decades, the handling of neonates has radically changed and the new guidelines highlight this growth and development. However, this area of skin care has lagged behind. One concern that remains is the issue of the toxic effects of ingredients found in water-based products like preservatives and fragrances. While it is possible that these may be toxic, this article will present evidence that the current skin care products that contain petrolatum and lanolin may be more toxic and potentially harmful. Further, using a product that is not preserved, yet occlusive, may in fact allow for microorganisms in colony forming units to multiply, thereby yielding systemic implications. The purpose of this article is to further illuminate these issues and to allow for greater understanding and discussion.

Skin is the largest organ of the body and provides protection between the body and its environment. In term babies, while there may be issues related to skin breakdown and infection, the stratum corneum is fully developed and protects the newborn. In contrast, the skin and skin barrier of a preterm neonate is not fully developed.

The skin of a premature neonate accounts for approximately thirteen (13) percent of its body weight. This compares to three (3) percent of body weight for adult skin. The body weight to skin ratio is four (4) times greater in the neonate when compared to an adult. As related specifically to skin care, these characteristics in neonate skin call into account:

• Fluid imbalances

• Percutaneous absorption of toxins

• Tissue injury

• Infection

The structure of adult skin is understood, while embryonic and neonate skin is not fully appreciated. Development of the skin within the uterus is complex and still under investigation. In utero, the skin undergoes two-dimensional growth to cover the surface area of the developing embryo and fetus. Premature neonate’s skin has not gone through full epidermal and dermal epidermal development.

In neonatal intensive care units (NICU) skin care product selection is carefully reviewed. With the risks outlined above, great care must be taken to ensure the wellbeing of the neonate within the first hours and days of life. Care of the skin is one of the most important areas of care for these at risk infants. Currently, NANN and AWHONN recommended a Aquaphor?, a petrolatum-based product as neonate skin care emollient.

In earlier work done at Stanford University, it was concluded that emollient cream moisturizer therapy of premature neonates decreases dermatitis without changing the microbiological flora. An emollient is an agent that softens or soothes skin. This definition is important because just as the standard-of-care has changed in NICUs over the past three decades, the selection of emollients has changed in the pharmaceutical industry.

High-tech silicone excipients have displaced petrolatum as companies have sought ways to improve treatment compliance traced to poor aesthetics associated with petrolatum-based formulations. Silicones are not new to the pharmaceutical industry. They are used in transdermal delivery systems, catheters and specialized medical devices, including pacemakers.

In a test to determine aesthetic benefits of silicone formulas over petrolatum-based formulas, 18 untrained volunteers were impaneled. They were asked to evaluate whether two products present any differences on individual sensory properties. The evaluation was conducted on the panelist’s forearms. Each panelist was asked to evaluate wetness, spreadability, speed of absorbance (not biologically, just feel), gloss, film residue, greasiness, silkiness and slip after perceived absorbance.

Figure I shows the silicone-containing formulation was perceived to be easier to spread and was clearly less tacky before and after absorption. A perceptible film was present on the skin for both formulations but the silicone-containing formulation was less greasy, silkier and more slippery (better lubrication) than petrolatum. The panelist’ perception of higher wetness for the silicone-containing formulation was attributed to its lower oiliness.

In a study conducted at a 48-bed NICU private hospital in Houston, Texas, to evaluate why the rate of systemic candidiasis (SC) per 1000 NICU patient-days increased from 5.1% in 1996 to17.4% in 1997 (a three-fold increase), it was determined that the increase in SC incidences was linked to the use of topical petrolatum ointment (TPO). In this well designed study, the investigators went on to hypothesize that TPO enhanced the adherence of C albicans to mucocutaneous surfaces. Also referenced in the study was a finding by Law S, et al, that unlike petrolatum, skin surface lipids inhibit adherence of candida albicans to stratum corneum.

By way of further examination, let’s more closely examine these two hypotheses. As observed in the Houston study, petrolatum enhanced adherence of C albicans to mucocutaneous surfaces. Petrolatum is known as an occlusive barrier. Occlusion is problematic because while it blocks TEWL, it also blocks cellular respiration necessary for barrier repair. Further, occlusion traps microorganisms under the petrolatum where they can breed in the moisture trapped therein. On the other hand, natural skin lipids, like omega 3-6 fatty acids, inhibit adherence of microorganisms to the stratum corneum.

Studies linking petrolatum to increased incidences of infections in preterm infants is ongoing and demonstrates mixed results. However, long term studies reflect a concern over the use of TPO protocols in NICUs. Petrolatum based ointments, like Aquaphor’s? twenty five year old formula, are the emollients of choice in NICUs. When one considers the changes in the standards of care in NICUs over the past three decades, perhaps now is the time to focus on new technologies in emollients that achieve skin care objectives without the aesthetic, epidermal challenges renders skin vulnerable to chemicals & infection, prevents normal TEWL & gland secretions, inhibits barrier repair, suppresses barrier recovery and reduces the epidermal proliferative response and microbial risk disadvantages of petrolatum.

To demonstrate the effectiveness of high products using molecular height silicones against petrolatum, Nutrashield TM was tested in a wash-off study against Aquaphor? and other leading skin barriers to determine each product’s ability to maintain skin protection after cleansing. As shown in Figure II, Nutrashield performed well against Aquaphor?, and did so while providing a breathable barrier instead of the occlusive barrier associated with Aquaphor? (a lanolin and petrolatum-based product). In clinical trials Nutrashield has proven effective in the treatment of skin breakdown in disordered and damaged skin, encountered in the wound care setting, as compared to previously available products.

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Based on the above results, Medline Nutrashield outperforms products containing petrolatum levels as high as 49%, and petrolatum combined with 15% Zinc Oxide. Additionally, both Sensi-Care 2 and Sween 24 also contain Dimethicone as an active ingredient (Sween at 6% versus 1% in the Nutrashield). The extended performance of the Nutrashield is most likely due to the addition of Divinyldimethicone/ Dimethicone Copolymer, which has an internal phase viscosity that is greater than 100,000,000 cst in viscosity. As it is delivered in an emulsion form, it is capable of laying down a thin, but consistent and robust film.

An in-vitro study at an independent laboratory was conducted, to determine the effectiveness of Nutrashield and Skin Repair Cream in reducing e-TEWL. Collagen samples were cut into 4×4 inch squares. Each square was pre-coated with 0.1 g of product. The product was applied by rubbing a finger over the collagen material to simulate actual use for a 20 second period. The product was then allowed to dry for five minutes. Each square was placed over Fisher Payne Permeability Cups, containing 3g of water. The samples were placed in a 37 degree oven and checked every four (4) hours. After 24 hours the cups were removed and a final weight was recorded.

Figure III shows that both REMEDY Nutrashield and REMEDY Skin Repair Cream were effective at reducing e-TEWL without occlusion. Nutrashield provided a fourfold reduction in e-TEWL over the control, while Skin Repair Cream showed a twofold improvement. The objective of topical skin care intervention is not to stop all TEWL, just excessive TEWL.

Skin care for neonates is an emerging science. But, since the reduced risk of infant mortality is paramount, improved emollient treatments deserve thoughtful consideration. Skin care for the high-risk neonate requires knowledge of the unique aspects and physiology of their skin. During the neonatal period many newborns develop preventable, clinically apparent skin problems and many more, especially preterm neonates, experience morbidity caused by compromised skin barrier integrity. Anatomical and physiological differences in the skin of premature and term infants place them at increased risk of skin injury and breakdown. All Children’s Hospital, St. Petersburg, FL, sent out a questionnaire to 482 NICU’s to learn how nurses describe and measure skin breakdown. Of the 45% that responded, it was reported that in extremely low birth weight (ELBW) infants, 21% suffered skin breakdown during the first week of life.

The reduction of microbial contamination and the protection against skin breakdown has been discussed. Another critical factor is TEWL associated with immature barrier in neonates is the rate of TEWL. A Swedish study calculated TEWL in infants 24 and 25 weeks of gestation maintained at an ambient relative humidity (RH) of 50%. The study found that TEWL on the first day after birth (58.4 +/-14.8g m(-2) h(-1) and remained at the same level during the second day. It then decreased significantly to 48.3+/-9.5 at postnatal age of day three. The use of a semipermeable skin care product like Nutrashield will reduce excessive TEWL by as much as fourfold.

Semipermeable dressings have been tested as a method to reduce TEWL in neonates to address skin breakdown and high fluid requirements common in ELBW infants. The studies revealed that semipermeable (breathable) barriers can be used safely on premature infants.

The use of ingredients perceived as “toxic” to neonates has limited the choices within the NICUs. Much of the literature points to preservatives and fragrances as falling into the “do-not-use” category. Both are found in the REMEDY products. Consideration of the potential toxicity of ingredients found in the “recommended” products may not have been fully clarified. This is interesting when one considers that lanolin and petrolatum, forming an occlusive barrier, are recommended. Let’s take a closer look at what is being recommended:

Lanolin originates as a secretion from the sebaceous glands in sheepskin. It is removed from the wool by scouring and high-speed centrifugal separators. Lanolin has had 33 alcohols and 36 fatty acids identified as constituents including aliphatic, steroid and triterpinoid alcohols; saturated nonhydroxylated, unsaturated nonhydroxylated and hydroxhlated acid. Commercial lanolin is allowed to have up to 40 parts per million (ppm) pesticide residues. However, it is not clear who monitors for this compliance.

Animal medicines, which include sheep dips for controlling lice and other parasites on sheep, are regulated by the Environmental Protection Agency (EPA). One of the common sheep dip ingredients is organochlorine (OC). This pesticide is based on the benzene ring with one or more chloride atoms attached and includes; DDT, lindane, dieldrin and aldrin. Other sheep dip pesticides include; synthetic pyrethroids, insect growth regulators, spinosyns, ivermectins and magnesium fluorosilicate. In 1994 in Wagga, NSW, a team of shearers successfully sued woolgrowers for allegedly endangering their health by improperly using chemicals. Shearers are becoming more aware of the potential risks associated with exposure to chemicals (sheep dip), particularly organophosphate group which can cause a serious nervous disorder.

There are about 26 pesticide residues found in commercial lanolin. The combined effect of pesticides acting by a common mechanism can be greater than the individual effect of any single pesticide. Since children are subject to non-dietary sources (like lanolin) of exposure pesticides, it is important to consider total exposure to pesticides from all sources combined. Nine hundred and ninety eight (989) references to lanolin and DDT were found in a Google search, April 2005.

La Leche League International is an important advocate for breastfeeding and their commitment has assured thousands of infants receive the vital nutrients found in colostrum and mother’s milk. While the organization acknowledges that toxins from the environment, including pesticides, show up in breast milk, the benefits outweigh the risks. However, the organization does recommend against topical use of commercial lanolin because of its pesticide content.

Petrolatum is a crude oil/petroleum fraction. Petroleum is a complicated mixture of chemicals, thought to have formed from the decay of ancient marine animals millions of years ago. Most of the constituents of petroleum are hydrocarbon molecules, oxygen, nitrogen, and sulfur atoms. The hydrocarbon atoms take principally four different forms; paraffins, olefins, cycloparaffins and aromatics. These constituents give us gasoline, kerosene, diesel fuel, lubricating oils (like mineral oil), petrolatum, asphalt and tar, to name a few.

During the manufacturing process, longer unbranched paraffin molecules are able to join together to form crystalline solids. These solids are called paraffin waxes. With time, paraffin waxes settle out of the lubricating oils and are usually removed. At lower temperatures, shorter unbranched paraffin molecules also settle out of lubrication oil. The semi-solid material that forms in cold lubricating oil is petrolatum or petroleum jelly.

The processing of petroleum into petrolatum removes varying amounts of toxins. The yellowish petrolatum has more residue than that of the white petrolatum. Two of the refining methods include sulphuric acid and earth filtering. The acid treatment and filtering is an old process still used to remove the impurities of the “cake” (petrolatum + technical oils). Another purification method is hydrogenation which pressurizes hydrogen through the hydrocarbons with the help of a specific catalyst.

Once one understands the source of petrolatum and why there is a risk of toxins, one must move on to a biologically more concerning issue. Petrolatum is occlusive. In an article by Fore, it was found that the degree of skin occlusion has an effect on barrier recovery. Occlusive products suppress barrier recovery and reduce the epidermal proliferative response to an abnormal stratum corneum barrier. An occlusive product, like petrolatum, will prevent TEWL and will slow the epidermal maturation and barrier repair. Occlusion of the skin increases the infectious organisms, potentially raising the skin’s pH. Occlusion will also directly increase the pH of the skin. Occlusive products also interfere with cellular respiration and may lead to cell death.

This information presents a powerful message that one may want to rethink the use of lanolin and petrolatum on neonate skin. The use of modern emollients like silicone, combined with natural omega 3-6 fatty acids, barrier-building amino acids and natural antioxidants and vitamins may deserve another look. Water-based skin care products are required by the Food and Drug Administration (FDA) to be preserved. This keeps them free of bacteria and protects the products from contamination when microorganisms from sources (like unclean hands) contaminate the product in the container as well as during use.

The requirement of preservatives and their use is not well understood. Preservatives are not optional in accordance with Food and Drug Administration (FDA) monographs covering the manufacturing of “Safe and Effective Drugs” or cosmetics. A manufacturer is required to perform a twenty eight (28) day preservative effectiveness challenge on its products and maintain a record of such testing for FDA inspections. Further, each batch requires proof that the batch meets microbial challenge requirements. Batches are tested in the tank, prior to filling, and then again at the beginning, middle and end of the filling process. This testing is done to ensure each product shipped is free of microbial contamination.

Since the use and safety of preservatives, especially parabens is under consideration in this article, comments from three regulating bodies are brought forward for consideration.

• The FDA recognizes parabens as a class of preservatives that have been used in a wide variety of foods, drugs, and cosmetics and that they keep products safe from microbial contamination. The Food, Drug, and Cosmetic Act require that cosmetics and non-prescription drugs and their individual ingredients must be safe and that labeling must be truthful and not misleading. The FDA can take immediate action to stop the sale of any product that does not meet its high standards. This includes the use of an effective preservative system.

• The European Food Safety Authority (EFSA) has reviewed the use of parabens in food and other products. The European Union (EU) Scientific Committee for Food (SCF) evaluated parabens in 1994 and established a temporary Acceptable Daily Intake (ADI) of 0-10mg/kg bw, as the sum of methyl, ethyl and propyl parabens. Further study also demonstrated that nooestrogenic activity took place in-vivo, and that there was no effect on forestomach cells in rats. In a teratogenicity study on 300 rabbits with oral does of methyl paraben, at doses of 550 mg/kg, no evidence of toxicity was found. The panel recognized that this dose far exceeded any anticipated oral dose.

• The Cosmetic, Toiletries, Fragrance Association (CTFA) is the body in the United States and through its Scientific Review Board, reviews all new cosmetic ingredients and assigns their INCI nomenclature (the required language found on packaging for all ingredients). The CTFA first studied the safety of parabens in 1984 and concluded they were safe as used in cosmetics. On November 14, 2004, as part of the normal re-review process, the CIR Expert Panel determined that it wanted to conduct a through review of the literature since the previous report in 1984. The safety of parabens has been once again reconfirmed.

Why then can there be a product that is not preserved? It is best that all products have some protection. However, some products that do not contain water can pass the challenge because microorganisms breed in water. Testing is done without the introduction of water. Consider this: a) an unpreserved product is placed on the skin, b) the product is occlusive, like petrolatum, c) the skin and its moisture, due to TEWL, contains microorganisms that are multiplying and trapped between the occlusive barrier and the skin, d) the skin care product on the skin is not preserved and now, e) a microorganism-rich moisture is being added. What are the consequences? Is there a systemic link and what is the potential sequela?

Toxins will be introduced to the neonate’s environment. They will come from mother’s milk, linens, clothing, human contact and a myriad of other sources. Careful consideration must always be given to the source of toxins and how multiple sources of them will impact the neonate. Product preservatives and fragrance are but two of these sources. The protection against e-TEWL and reducing the risks of systemic infections are worth considering when making neonate skin care choices.

Nutrashield from Medline Industries, Inc. is a semipermeable emollient barrier cream that:

• has excellent wash-off characteristics

• may reduce the incidence of colony forming microorganisms in the neonate population associated with petrolatum

• offers excellent aesthetic benefits including spreadability.

Additional creams and lotions in the REMEDY product line provide semipermeable barriers and nourish the skin37. Further research is necessary to confirm the product’s suitability in NICUs.

Article by Darlene McCord, Ph.D.

Dr. Darlene E McCord is one of the two founders of McCord Research. As senior researcher, she brings a unique blend of scientific credentials to the position. Through her leadership, the company has achieved worldwide recognition in the OTC Drug and Medical Device categories. Her field of specialty is corneotherapy, focusing on the transport of small molecules across the stratum corneum for treatment of skin disorders associated with distressed and wounded skin. Dr. Darlene E McCord is widely published on subjects related to immunodermatology and corneotherapy.

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